The Maternal Health Research Centers of Excellence include ten Research Centers, a Data Innovation and Coordination Hub, and an Implementation Science Hub. Together, these institutions will work to design and conduct research projects to address the biological, behavioral, environmental, socio-cultural, and structural factors that affect pregnancy-related complications and deaths. They will focus on populations that experience health disparities, including racial and ethnic minorities, socioeconomically disadvantaged populations, those living in underserved rural areas, sexual and gender minority populations, and people with disabilities. In addition to conducting research projects and building community partnerships, the Centers of Excellence will support training and professional development, prioritizing early-stage investigators and those from backgrounds or identities currently underrepresented in the health sciences.